Biomedical research is rapidly expanding in terms of new scientific techniques and model systems, as well as new ethical challenges. Advanced scientific studies have unraveled intricate mechanisms of disease, leading to development of novel treatments and therapies that prevent or mitigate human suffering. The utilization of various tissues, cells, and models helps to facilitate these advances, but science that relies on human embryos and aborted fetal tissue for experimentation is fraught with ethical concerns, especially in light of numerous ethical alternatives available to researchers.

Furthermore, genetic analysis, diagnosis and screening have become available both earlier in life, during the first weeks in the womb or even for the embryo in the laboratory dish, and in simpler ways such as from a drop of the mother’s blood. Such developments have raised the prospects for potential medical applications to treat genetic diseases, but also heightened concerns about designer children or genetic alterations and enhancements.

CLI carefully analyzes advanced technologies such as these, advocating for sound public policy and responsible application of developed techniques using non-controversial alternatives, so that the science is never abused for eugenic or life-destroying ends.

A Handbook of Bioethical Considerations Regarding Nascent Human Beings and Their Cells (Handbook II)

James L. Sherley, M.D., Ph.D., Tara Sander Lee, Ph.D.   

This is Issue 10 in CLI’s On Science Series. To view this report as a PDF, see: A Handbook of Bioethical Considerations Regarding Nascent Human Beings and Their Cells (Handbook II)   This handbook is a companion to “Handbook of Nascent Human Beings: A Visual Aid for Understanding the Science and Experimentation (Handbook I)“   […]

Handbook of Nascent Human Beings: A Visual Aid for Understanding the Science and Experimentation

Tara Sander Lee, Ph.D., James L. Sherley, M.D., Ph.D.   

Originally published February 25, 2022 and updated July 7, 2022 to include companion Table 1   This is Issue 8 in CLI’s On Science series. To view this report as a PDF, see: Handbook of Nascent Human Beings: A Visual Aid for Understanding the Science and Experimentation. To view the companion paper, please see: “Handbook […]

‘The Amazon Of Baby Body Parts’

Charlotte Lozier Institute  

Pro-Life Activists Say They Discovered Fetuses Stored in Paper Bags at University of Washington   Washington, D.C. – A disturbing photograph released Wednesday reportedly show human fetuses stored in paper bags inside a freezer at the University of Washington Birth Defects Research Laboratory in Seattle.  The photographs were taken by Progressive Anti-Abortion Uprising, Survivors of […]

ISSCR’s Reversal of the 14-Day Rule

Charlotte Lozier Institute  

Society sits on the cusp of some of the few remaining battles threatening to permanently alter the course of bioethical history; if these battles are not engaged, the proposed changes in bioethics will make acceptable atrocities upon human dignity the magnitude of which can only be imagined.

lab rat

Human Embryos as Lab Rats

Charlotte Lozier Institute  

“At a time when Americans are increasingly urged to ‘follow the science,’ the ISSCR tarnishes the image of science by showcasing deeply unethical scientific practices,” said Dr. David Prentice, vice president and research director at CLI. 

CLI Comment: HHS Proposed Rule Fetal Tissue Regulations

David Prentice, Ph.D., Tara Sander Lee, Ph.D.   

The trafficking of aborted baby body parts for research is barbaric. The Trump administration was dedicated to ending this practice and protecting the sanctity of human life. Grave injustices were exposed that exploited unborn children for experimentation, but were not fully remedied.   Policy changes brought an immediate halt to federal contracts that trafficked organs […]

CLI Responds to Calls to Drop “14-Day Limit” on Growing Human Embryos

Charlotte Lozier Institute  

Human embryos should not be grown for research, manipulated like mice in a lab, or used instrumentally at all. Those who care about the sanctity of life support a zero-day limit that will preserve respect for every human life and refrain from exploitation of or injury to human subjects.

CLI Statement on Johnson & Johnson Vaccine: Abortion-Derived Cell Lines Used in Production Process

Charlotte Lozier Institute  

“For many Americans, the approval of Johnson & Johnson’s vaccine raises renewed questions about the use of cells derived from elective abortions. Many leading vaccine candidates supported by Operation Warp Speed, including the approved vaccines produced by Pfizer/BioNTech and Moderna, do not use abortion-derived cell lines in their production. Unlike the majority of those candidates, Johnson & Johnson does use these cell lines in the production process.

Cell Lines Used for Viral Vaccine Production

Charlotte Lozier Institute  

Vaccines Licensed for Use in the United States by the Food and Drug Administration (FDA)   Current FDA list accessed 4 January 2021   View this chart as a PDF here   Use of Cell Lines for Vaccine Production  🟩 No fetal cells  🔺 fetal cells —  no cell lines – bacteria grow independently Vaccine […]

What you need to know about the COVID-19 vaccines

David Prentice, Ph.D., Tara Sander Lee, Ph.D.   

Last updated June 2, 2021   Most COVID-19 Vaccines Do Not Use Fetal Cells for Production; Several Used Abortion-Derived Cell Lines in Testing; Experts Urge All Vaccine Developers to Use Noncontroversial Alternatives   View short chart View full chart Charlotte Lozier Institute (CLI) has published a new chart (en español) detailing whether the eight leading […]

Análisis del Instituto Charlotte Lozier (CLI): La mayoría de las vacunas de la Operation Warp Speed no se producen usando células derivadas de abortos

Charlotte Lozier Institute  

Comunicado de prensa INMEDIATO: 3 de diciembre de 2020. Contacto: Prudence Robertson,, 240-672-2828   Varias líneas celulares derivadas del aborto se utilizan en pruebas; los expertos instan a todos los desarrolladores de vacunas a utilizar alternativas no controversiales   Washington, D.C. – Hoy el Instituto Charlotte Lozier (CLI) ha publicado un nuevo gráfico que […]

CLI Analysis: Majority of Operation Warp Speed Vaccines Not Produced Using Abortion-Derived Cells

Charlotte Lozier Institute  

FOR IMMEDIATE RELEASE: December 3, 2020 Contact: Prudence Robertson,, 240-672-2828   Several Used Abortion-Derived Cell Lines in Testing; Experts Urge All Vaccine Developers to Use Noncontroversial Alternatives Washington, D.C.  – Today Charlotte Lozier Institute (CLI) published a new chart detailing whether the eight leading COVID-19 vaccine candidates supported by Operation Warp Speed are produced or […]

Federal Bioethics Commissions and Bias Against the Unborn

Richard Doerflinger, M.A.  

This is Issue 17 in The American Reports Series. The paper may be viewed as a PDF here: Federal Bioethics Commissions and Bias Against the Unborn   In August, the Trump administration’s new Human Fetal Tissue Research Ethics Advisory Board reviewed requests made to the National Institutes of Health (NIH) for federally funded fetal tissue […]

Update: COVID-19 Vaccine Candidates and Abortion-Derived Cell Lines

David Prentice, Ph.D.  

To view this chart as a PDF, see: COVID-19 Vaccine Candidates and Abortion-Derived Cell Lines   Updated June 2, 2021   Accurate information about the development and production of COVID-19 vaccines is essential, especially because many proposed candidates use newer molecular technologies for production of a viral vaccine. One concern regarding the ethical assessment of […]

Designing Babies: Science, Ethics, and Policies of a Post-Genomic Era

Tara Sander Lee, Ph.D., David Prentice, Ph.D.   

At the Center for Bioethics and Human Dignity annual summer conference “Bioethics in Real Life,” Dr. David Prentice and Dr. Tara Sander Lee presented a workshop entitled Designing Babies: Science, Ethics, and Policies of a Post-Genomic Era.   Scientific advancements in the fields of genetics, molecular diagnosis, and genetic engineering were introduced so that participants […]

Muestra de la infección viral y la producción de vacunas

David Prentice, Ph.D., Tara Sander Lee, Ph.D.   

Como resultado de la rápida propagación del nuevo coronavirus, técnicamente conocido como SARS-CoV-2, los gobiernos de Estados Unidos y de otros paises han pasado por varios intentos fallidos en la producción de una vacuna efectiva contra esta enfermedad que se transmite tan rápidamente.  Ha surgido una selección de candidatos para esta vacuna  y se encuentran en distintas etapas de desarrollo y de prueba.  Al mismo tiempo, se han manifestado otras preguntas acerca de la manera en la cual estas vacunas son producidas; inlcuyendo los procesos sobre los cuales millones de americanos tienen objeciones en material moral.  Hoy en día, la variedad de medios utilizados para producir vacunas es inmensa; en algunos casos son éticament lícitas, mientras que en otros los procedimientos que utilizan son questionables.  Para ayudar a la comprensión de estos modos de producción, ofrecemos una guía básica respecto a la ciencia involucrada.

Video: Multiple Sclerosis Survivor Thriving Six Years after Adult Stem Cell Transplant

Charlotte Lozier Institute  

May 30 marked World Multiple Sclerosis Day, a day to bring together the global MS community, raise awareness, and share stories. In a new patient video released by the Charlotte Lozier Institute’s Stem Cell Research Facts project, multiple sclerosis survivor Allison Carr shares about her journey of thriving and encouraging others six years after her […]

Charlotte Lozier Institute Responds to Claim that Aborted Baby Parts Are Needed to Develop COVID-19 Treatment

Charlotte Lozier Institute  

Washington, D.C. – In response to news reports claiming that potential treatments for coronavirus will not be discovered unless the body parts of aborted children are used in experiments, the Charlotte Lozier Institute (CLI) issued the following comment: “Those who advocate experimentation using body parts harvested from aborted children are shamelessly exploiting the coronavirus pandemic, […]

Lozier Institute on Gene-Editing: Focus on Helping Patients, Not Creating Designer Babies

Charlotte Lozier Institute  

As the scientific community weighs the risks and rewards of CRISPR, a controversial gene-editing tool, scientists in New York City are moving forward with experiments changing DNA on human sperm. In response to these new germline (heritable) experiments and the broader conversation surrounding CRISPR, Charlotte Lozier Institute (CLI), the research and education arm of Susan B. […]

CLI Announces New Senior Fellow and Director of Life Sciences

Katey Price, J.D.  

  Today, the Charlotte Lozier Institute (CLI), the education and research arm of national pro-life group Susan B. Anthony List (SBA List), announced that associate scholar Tara Sander Lee, Ph.D. will transition to a larger role as CLI’s Senior Fellow and Director of Life Sciences.   CLI president Charles A. “Chuck” Donovan, said:   “During […]

CLI Scientists Respond to Letter on Genetically Modified Children: Not Enough

Charlotte Lozier Institute  

FOR IMMEDIATE RELEASE: March 14, 2019 Contact: Nicole Stacy,, 202-223-8073   Washington, D.C. – Yesterday 18 scientists representing seven countries published a letter calling for a “global moratorium on all clinical uses of human germline editing — that is, changing heritable DNA (in sperm, eggs or embryos) to make genetically modified children.” Charlotte Lozier […]

The Future of IVF’s Genetic Testing?

Caroline Funk  

In opening scenes of the sci-fi thriller Gattaca, the viewer meets a couple who decides to conceive their second child by In Vitro Fertilization (IVF), which has become the “natural” method in this futuristic society. They are told by the scientist who created, screened, and edited the DNA of their embryos, “This child is still […]

Adult Stem Cells and Gene Therapy Save a Young Boy

David Prentice, Ph.D.  

When people talk about something that “saved their skin,” they usually mean that it helped them out of a difficult situation. But a young boy in Germany has literally had his skin—and his life—saved through the use of genetically-engineered adult stem cells. The boy suffered from a condition called junctional epidermolysis bullosa, a severe and […]

Fact Sheet: Responses Regarding Poor Prenatal Diagnosis

Charlotte Lozier Institute  

This fact sheet outlines the various responses to a “poor prenatal diagnosis” for a fetal abnormality, noting especially recent medical advances well as the life-affirming option for perinatal hospice.

Seeking Pro-life Leadership at the National Institutes of Health

David Prentice, Ph.D.  

In a recent op-ed, Dr. David Prentice and Congressman Jim Banks argue that it’s time for a change in leadership at the National Institutes of Health: Dr. Francis Collins has not shown any pro-life leadership at the National Institutes of Health (NIH). In fact, in an interview, Dr. Collins‘ response to a congressional letter outlining pro-life members’ […]

Q&A with the Scholars: Science, Ethics, and Fetal Tissue

Charlotte Lozier Institute  

Tara Sander Lee, Ph.D., is a Molecular and Cell Biologist with over 15 years of experience in academic research and healthcare. In this interview, she discusses genetic testing for diagnosis and treatment of children and the ethical and scientific issues surrounding the use of fetal tissue procured from abortion for research.

Q&A with the Scholars: Down Syndrome and Prenatal Testing

Charlotte Lozier Institute  

I believe that the decision to abort is responsible for far more sadness and family difficulties than the acceptance of a child with Down syndrome who truly does bring a family’s capacity for love to a whole new level.

CLI Comment on NIH Proposal to Fund Human-Animal Chimeras

David Prentice, Ph.D.  

The U.S. National Institutes of Health (NIH) has proposed lifting a ban on approval and funding for the creation of human-animal chimeras. CLI submitted detailed comments regarding the science and ethics of such research, opposing the NIH proposal and noting ethical and scientifically valid alternatives exist to satisfy scientific demands.

Nature Journal on Embryo Gene Manipulation: “It’s Time to Give Patients a Voice”

Genevieve Plaster, M.A.  

As the international debate continues on the use of CRISPR gene-manipulating technology on human embryos, Nature journal this week gave serious consideration to concerns about its societal consequences. In a news feature entitled, “Should you edit your child’s genes?” author Erika Check Hayden takes a refreshingly humane approach by asking people with disabilities what they think of the real-life prospect of “editing out” genes responsible for disability before a person is even born.

“3-Parent Embryos” and “Gene-Edited Babies”: A Visual Aid

David Prentice, Ph.D.  

As both international and national debates continue over the ethics and science of “three-parent embryos” and “genetically modified embryos”, Dr. David A. Prentice, Ph.D. of the Charlotte Lozier Institute has prepared a series of visual primers for the general public, illustrating the various methods by which germline genetic engineering is used to create genetically modified human embryos.

North Carolina Eugenics Victims Still Seeking Justice due to Compensation Technicality

Genevieve Plaster, M.A.  

Debra Blackmon was 13 years old when two social workers visited her home in North Carolina, assessed her to be “severely retarded,” and put in motion the process for her sterilization. The year was 1972. Though the state passed a law in 2013 to compensate victims of involuntary sterilization under the North Carolina Eugenics Board, Blackmon was denied because her paperwork stated that she was sterilized under county authority – not state authority, a technicality written into the law.

Brave New Britain: The U.K. Approves Production of Three-Parent Embryos

David Prentice, Ph.D.  

The concept of “designer babies” may sound like science fiction, a literal Brave New World, but it is decidedly not fictional – it is here now and being pushed rapidly into fertility clinics.

After only a brief debate today in the House of Commons, British Members of Parliament (MPs) approved a proposal to create genetically-engineered babies who contain the DNA of three parents: two mums and a dad. The vote to approve wasn’t even close – 382 ayes to 128 noes.

Ohio Passes Down Syndrome Bill Requiring Healthcare Professionals to Provide Support Information to Parents

Genevieve Plaster, M.A.  

On December 19, Ohio passed the Down Syndrome Information Act, which requires medical professionals to distribute up-to-date, evidence-based information on Down syndrome to parents who receive the diagnosis, either prenatally or after birth, that their child has Down syndrome (DS). Included in the required material is contact information for support organizations and local resources available to the parents. The Down Syndrome Information Act (Sub. HB 552), sponsored by Rep. Peter Stautberg, was signed into law along with 39 other pieces of legislation by Governor John Kasich last Friday. The bill passed the House and Senate both times with no opposing votes this November and mid-December.

Non-invasive Prenatal Screening Expands Disability Discrimination Abortion

Nora Sullivan, M.P.A  

A recent report on prenatal genetic screening from the New England Center for Investigative Reporting has caused quite a stir. The report showed significant inaccuracies in non-invasive (i.e., using blood tests and not invasive means such as chorionic villus sampling and amniocentesis) prenatal screening and told the stories of a number of women who chose to terminate based on these inaccurate test results. The report, which is the result of a three-month investigation by the group, found that prenatal testing companies are overselling the accuracy of their screening tests and doing little to inform parents and doctors of the major risk of unreliability of these test results – a circumstance that can lead to a multitude of problems.

The United Kingdom’s Rubicon on Three-Parent Embryos

Nora Sullivan, M.P.A  

Later this month, leading scientists from around the world are set to caution a UK parliamentary inquiry against the creation of babies using the genetic material of three parents. On October 22, this group will warn the inquiry against such genetic engineering and the possible scientific and ethical problems it could bring.

Improving Joyful Lives: Society’s Response to Difference and Disability

Charlotte Lozier Institute  

This paper looks at the highly complex genetic condition that is Down syndrome and society’s response to individuals with this condition. This important paper points out that while research to improve the lives of those with Down syndrome has progressed, federal funding for it lags considerably behind that for other genetic disorders. Policy recommendations are made for the support of those with this condition and their families.

Cloning is Cloning is Cloning

Eugene C. Tarne  

This primer on cloning examines the nature and purpose of human cloning in light of recent developments in stem cell technology. The paper points out that all cloning is reproductive and reflects on the immediate outcome of human cloning – a human embryo – while examining the terminology used by cloning advocates to obscure the facts.

Victims of NC Eugenics Program to Receive Compensation At Last

Nora Sullivan, M.P.A  

Despite signals earlier this year that the State of North Carolina would once again not include plans compensation for the victims of the state’s infamous eugenics programs in the state’s budget, it seems that those who suffered forcible or coerced sterilization at the hands of the state will see some restitution after all as North […]

UK Government Panel Approves Genetically Engineered “Three-Parent” Embryos

Eugene C. Tarne, Private: Jennifer Lahl, R.N., M.A.   

Great Britain’s Human Fertilisation and Embryology Authority (HFEA), which oversees fertility treatments and embryo research in that nation, recently approved fertility procedures that would amount to the genetic engineering of children through cloning (nuclear transfer) technology and germ-line modification, resulting in a “three-parent embryo” that would have genetic material from two mothers and one father.

Possible Adult Stem Cell Therapy for Blood-Disorders in Down Syndrome

Eugene C. Tarne  

A recent study from researchers at the University of Washington announced a major step forward in the treatment of genetic diseases and specifically in treating Down syndrome patients.     Down syndrome occurs when there is an extra copy of chromosome 21 (hence its alternative name, Trisomy 21) in the individual’s genetic makeup, causing the physical and mental […]

Justice for Eugenics Victims in North Carolina

Nora Sullivan, M.P.A  

The state of North Carolina has now identified more than 100 victims of their massive state-sponsored eugenics program which lasted from 1929 to 1974 according to reports out recently.  In an effort to compensate for the wrongs of the past, Demoicratic Gov. Bev Perdue established the N.C. Justice for Sterilization Victims Foundation.  The foundation seeks to provide justice […]