Cell Lines Used for Viral Vaccine Production

Charlotte Lozier Institute  

Vaccines Licensed for Use in the United States by the Food and Drug Administration (FDA)

 

Current FDA list accessed 4 January 2021

 

View this chart as a PDF here

 

Use of Cell Lines for Vaccine Production

 🟩 No fetal cells
Β πŸ”Ί fetal cells

— Β no cell lines – bacteria grow independently

Vaccine Product Name
(linked to FDA vaccine page
including package insert)
Vaccine Trade Name
πŸ”Ί WI-38 Adenovirus Type 4 and Type 7 Vaccine, Live, Oral No Trade Name
Anthrax Vaccine Adsorbed Biothrax
BCG Live BCG Vaccine
BCG Live TICE BCG
Cholera Vaccine Live Oral Vaxchora
🟩 Vero Dengue Tetravalent Vaccine, Live DENGVAXIA
Diphtheria & Tetanus Toxoids Adsorbed No Trade Name
Diphtheria & Tetanus Toxoids & Acellular Pertussis Vaccine Adsorbed Infanrix
Diphtheria & Tetanus Toxoids & Acellular Pertussis Vaccine Adsorbed DAPTACEL
🟩 Yeast (HepB)

🟩Vero (polio)

— diphtheria, tetanus, pertussis

Diphtheria & Tetanus Toxoids & Acellular Pertussis Vaccine Adsorbed, Hepatitis B (recombinant) and Inactivated Poliovirus Vaccine Combined Pediarix
🟩 Vero (polio)

— diphtheria, tetanus, pertussis

Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed and Inactivated Poliovirus Vaccine KINRIX
🟩 Vero (polio)

— diphtheria, tetanus, pertussis

Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed and Inactivated Poliovirus Vaccine Quadracel
🟩 Yeast (HepB)

🟩 Vero (polio)

— diphtheria, tetanus, pertussis, haemophilus

Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed, Inactivated Poliovirus, Haemophilus b Conjugate [Meningococcal Protein Conjugate] and Hepatitis B [Recombinant] Vaccine VAXELIS
🟩 Vero (polio)

— diphtheria, tetanus, pertussis, haemophilus

Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed, Inactivated Poliovirus and Haemophilus b Conjugate (Tetanus Toxoid Conjugate) Vaccine Pentacel
🟩 Vero Ebola Zaire Vaccine, Live ERVEBO
Haemophilus b Conjugate Vaccine (Meningococcal Protein Conjugate) PedvaxHIB
Haemophilus b Conjugate Vaccine (Tetanus Toxoid Conjugate) ActHIB
Haemophilus b Conjugate Vaccine (Tetanus Toxoid Conjugate) Hiberix
πŸ”Ί MRC-5 Hepatitis A Vaccine, Inactivated Havrix
πŸ”Ί MRC-5 Hepatitis A Vaccine, Inactivated VAQTA
πŸ”Ί MRC-5 (HepA)

🟩 Yeast (HepB)

Hepatitis A Inactivated and Hepatitis B (Recombinant) Vaccine Twinrix
🟩 Yeast Hepatitis B Vaccine (Recombinant) Recombivax HB
🟩 Yeast Hepatitis B Vaccine (Recombinant) Engerix-B
🟩 Yeast Hepatitis B Vaccine (Recombinant), Adjuvanted HEPLISAV-B
🟩 Yeast Human Papillomavirus Quadrivalent (Types 6, 11, 16, 18) Vaccine, Recombinant Gardasil
🟩 Yeast Human Papillomavirus 9-valent Vaccine, Recombinant Gardasil 9
🟩 Insect cells Human Papillomavirus Bivalent (Types 16, 18) Vaccine, Recombinant Cervarix
🟩 Chicken eggs Influenza A (H1N1) 2009 Monovalent Vaccine No Trade Name
🟩 Chicken eggs Influenza A (H1N1) 2009 Monovalent Vaccine No Trade Name
🟩 Chicken eggs Influenza A (H1N1) 2009 Monovalent Vaccine No Trade Name
🟩 Chicken eggs Influenza A (H1N1) 2009 Monovalent Vaccine No Trade Name
🟩 Chicken eggs Influenza A (H1N1) 2009 Monovalent Vaccine No Trade Name
🟩 Chicken eggs Influenza Virus Vaccine, H5N1 (for National Stockpile) No Trade Name
🟩 Chicken eggs Influenza A (H5N1) Virus Monovalent Vaccine, Adjuvanted No Trade Name
🟩 MDCK cells Influenza A (H5N1) Monovalent Vaccine, Adjuvanted AUDENZ
🟩 Chicken eggs Influenza Vaccine, Adjuvanted FLUAD QUADRIVALENT
🟩 Chicken eggs Influenza Vaccine, Adjuvanted FLUAD
🟩 Chicken eggs Influenza Vaccine AFLURIA QUADRIVALENT
🟩 MDCK cells Influenza Vaccine Flucelvax Quadrivalent
🟩 Chicken eggs Influenza Virus Vaccine
(Trivalent, Types A and B)
Afluria
🟩 Chicken eggs Influenza Virus Vaccine
(Trivalent, Types A and B)
FluLaval
🟩 Chicken eggs Influenza Vaccine, Live, Intranasal
(Trivalent, Types A and B)
FluMist
🟩 Chicken eggs Influenza Virus Vaccine
(Trivalent, Types A and B)
Fluarix
🟩 Chicken eggs Influenza Virus Vaccine
(Trivalent, Types A and B)
Fluvirin
🟩 Chicken eggs Influenza Virus Vaccine
(Trivalent, Types A and B)
Agriflu
🟩 Chicken eggs Influenza Virus Vaccine
(Trivalent, Types A and B)
Fluzone, Fluzone High-Dose and Fluzone Intradermal
🟩 MDCK cells Influenza Virus Vaccine
(Trivalent, Types A and B)
Flucelvax
🟩 Insect cells Influenza Vaccine (Trivalent) Flublok
🟩 Insect cells Influenza Vaccine (Quadrivalent) Flublok Quadrivalent
🟩 Chicken eggs Influenza Vaccine, Live, Intranasal
(Quadrivalent, Types A and Types B)
FluMist Quadrivalent
🟩 Chicken eggs Influenza Virus Vaccine
(Quadrivalent, Types A and Types B)
Fluarix Quadrivalent
🟩 Chicken eggs Influenza Virus Vaccine
(Quadrivalent, Types A and Types B)
Fluzone Quadrivalent
🟩 Chicken eggs Influenza Vaccine Flulaval Quadrivalent
🟩 Vero Japanese Encephalitis Virus Vaccine, Inactivated, Adsorbed Ixiaro
🟩 Chick cells (Measles, Mumps)

πŸ”Ί WI-38 (Rubella)

Measles, Mumps, and Rubella Virus Vaccine, Live M-M-R II
🟩 Chick cells (Measles, Mumps)

πŸ”Ί WI-38 (Rubella)

πŸ”Ί MRC-5 (Varicella-Zoster)

Measles, Mumps, Rubella and Varicella Virus Vaccine Live ProQuad
Meningococcal (Groups A, C, Y, and W-135) Oligosaccharide Diphtheria CRM197 Conjugate Vaccine Menveo
Meningococcal (Groups A, C, Y and W-135) Polysaccharide Diphtheria Toxoid Conjugate Vaccine Menactra
Meningococcal Group B Vaccine BEXSERO
Meningococcal Group B Vaccine TRUMENBA
Meningococcal Polysaccharide Vaccine, Groups A, C, Y and W-135 Combined Menomune-A/C/Y/W-135
Meningococcal (Groups A, C, Y, W) Conjugate Vaccine MenQuadfi
Plague Vaccine No trade name
Pneumococcal Vaccine, Polyvalent Pneumovax 23
Pneumococcal 13-valent Conjugate Vaccine
(Diphtheria CRM197 Protein)
Prevnar 13
Poliovirus Vaccine Inactivated (Human Diploid Cell) Poliovax (discontinued in U.S.)
🟩 Vero Poliovirus Vaccine Inactivated (Monkey Kidney Cell) IPOL
πŸ”Ί MRC-5 Rabies Vaccine Imovax
🟩 Chicken cells Rabies Vaccine RabAvert
🟩 Monkey cells Rabies Vaccine Adsorbed No Trade Name
🟩 Vero Rotavirus Vaccine, Live, Oral ROTARIX
🟩 Vero Rotavirus Vaccine, Live, Oral, Pentavalent RotaTeq
🟩 Chicken cells Smallpox and Monkeypox Vaccine, Live, Non-Replicating JYNNEOS
🟩 Vero Smallpox (Vaccinia) Vaccine, Live ACAM2000
Tetanus & Diphtheria Toxoids, Adsorbed TDVAX
Tetanus & Diphtheria Toxoids Adsorbed for Adult Use TENIVAC
Tetanus Toxoid Adsorbed No Trade Name
Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine, Adsorbed Adacel
Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine, Adsorbed Boostrix
Typhoid Vaccine Live Oral Ty21a Vivotif
Typhoid Vi Polysaccharide Vaccine TYPHIM Vi
πŸ”Ί MRC-5 Varicella Virus Vaccine Live Varivax
🟩 Chicken eggs Yellow Fever Vaccine YF-Vax
πŸ”Ί MRC-5 Zoster Vaccine, Live, (Oka/Merck) Zostavax
🟩 CHO cells Zoster Vaccine Recombinant, Adjuvanted SHINGRIX

 

 | 

Sign up to receive email updates from the Charlotte Lozier Institute.