Week 1 to 2

Implantation and beginning of nourishment

Human Prenatal Age
  • PCW 2
  • Days 7-13
  • Gestational Week 4
  • The hollow ball of embryonic cells, called the blastocyst, implants in the lining of the mother’s uterus.

  • The inner cells in the blastocyst form the structures and organs of the body and the outer cells help form the connection between the mother and embryo – the placenta and embyronic membranes.

  • By the end of the second week, the embryo usually creates enough of the hormone hCG to detect the pregnancy with a home pregnancy test.

Implantation takes a couple of days. Six days after conception, the blastocyst attaches to the mother’s uterine wall, called the endometrium. The blastocyst spends the next few days embedding completely into the endometrium.

Once the blastocyst implants into the uterine wall, this embryo begins receiving nourishment from the mother. The cells on the outside of the blastocyst, called the trophoblasts, facilitate the implantation into the mother’s endometrium. These embryonic cells form the placenta and umbilical cord.1 During the second week, the embryo forms a yolk sac from some of the inner cells of the blastocyst. The embryo’s first blood cells and future reproductive cells form in the yolk sac. Later, the yolk sac becomes part of the lining of the digestive system.2

Medical art. A blastocyst begins implanting in the wall of the uterus. (Image Credit: Science Source)

The pre-placental cells of the pregnancy, called trophoblasts, start producing a hormone called human chorionic gonadotropin hormone, or hCG. This is the hormone detected in home pregnancy tests. The embryo’s trophoblasts produce enough hCG to detect with a home pregnancy test about 11 days after conception.3 HCG prompts the corpus luteum, which is the cyst in the mother’s ovaries where the egg was released, to make progesterone. Progesterone stops the mother’s menstrual cycle and maintains the lining of the uterus – allowing pregnancy to continue.4

Dive Deeper
Some disorders, like color blindness and hemophilia, are controlled by genes on the X-chromosome...
Sperm-egg fusion