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Charlotte Lozier Institute

Phone: 202-223-8073
Fax: 571-312-0544

2776 S. Arlington Mill Dr.
#803
Arlington, VA 22206

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Charlotte Lozier Institute

Phone: 202-223-8073
Fax: 571-312-0544

2776 S. Arlington Mill Dr.
#803
Arlington, VA 22206

Weeks 19 & 20

Responding to sound

Human Prenatal Age
  • Post-conception week 17&18
  • 5 Months Pregnant
  • Gestational Weeks 19&20
Highlights
  • In week 19, some unborn babies open their mouths before bringing their hands there, showing predictive awareness of their movements in the womb.1

  • The earliest evidence of an unborn baby responding to sound is at 19 weeks.2 By 20 to 21 weeks, about half of unborn babies respond to a tone with a change in heartrate.3

  • By 20 weeks, the unborn baby’s vocal cords may vibrate as if he is crying.4

Fetal behavior shows signs of emerging sophistication. Around 19 weeks, the baby shows early awareness of his own movement, often opening his mouth before bringing his hands to it, as if anticipating the action.5 By 20 weeks, the vocal cords can move in patterns similar to those used during a newborn’s cry after birth.6

This composite image rendered from light-guided endoscopy recordings shows the fetus alive in the uterus 5 months after [tooltip anchor="fertilization"]Sperm-egg fusion[/tooltip]. By week 20, the baby's vocal cords may vibrate as if he is crying. The unborn baby may also respond to loud noises. (Image Credit: <a href="https://erf.science/#high-resolution">Education Resource Fund</a>)
This composite image rendered from light-guided endoscopy recordings shows the fetus alive in the uterus 5 months after fertilization. By week 20, the baby's vocal cords may vibrate as if he is crying. The unborn baby may also respond to loud noises. (Image Credit: Education Resource Fund)
Evidence that the unborn experiences pain

No one knows exactly when the fetus starts feeling pain, but scientists infer when the fetus feels pain using three main measures: 

  1. Ultrasounds of fetal facial expressions. The earliest recorded grimace in response to a painful injection came from a 23-week fetus.7
  2. Increases in the circulating stress hormones in a fetus’s bloodstream. The earliest recordings showing that the baby’s stress hormones increase after a painful blood transfusion come from unborn babies as young as 18 weeks. 8 9 10 11 12 13
  3. The existence of pain sensors in the fetal skin that connect to brain circuits. By examining the connections between neurons, and the growth of brain structures that process pain in adults, researchers can predict when the fetus starts responding to pain. Cutting-edge research and reviews of peer-reviewed literature have demonstrated that the unborn baby may start feeling pain as early as 12 weeks, and with considerable evidence by 15 weeks.14 15

Even more of the brain connections for processing pain have developed by 20 weeks. Specifically, neural connections between the brain and the rest of the body are functionally complete after 18 weeks.16 Furthermore, two important brain structures for processing pain include the diencephalon and the thalamus. The diencephalon is sufficiently developed at 15 weeks to create a pain experience,17 and the thalamus is sufficiently developed at 17 weeks to transmit pain information.18 19   

Information from all the senses, except smell, makes a neural connection in the thalamus before moving to the cortex for further processing. Decision making, perception, and language are all controlled by the cortex. None of these skills are fully developed at birth, and neither is their underlying brain structure. Before the cortex starts forming, a transitional structure called the subplate forms. This temporary and functional structure can be found in the developing brain between 12 and 35 weeks and has the capacity to process some pain information.20 21 Taken together, the current science shows that the fetus can feel pain well before 20 weeks.

The human brain at 20 weeks. All the connections are in place to process pain. (Image Credit: Science Source)
The human brain at 20 weeks. All the connections are in place to process pain. (Image Credit: Science Source)
How much amniotic fluid does the fetus swallow in the womb?

By about 14 weeks, the fetus begins making rhythmic jaw movements followed by swallowing—clear signs that he is drinking amniotic fluid. These early swallows help regulate the amount of amniotic fluid and carry flavor and scent molecules past the developing tongue and nose, gently training the senses of taste and smell. 22

The amount of amniotic fluid the baby drinks steadily increases. At 16 weeks, he swallows between 2 and 7 milliliters per day, rising to 13 to 16 milliliters by 20 weeks. 23 By the final month of pregnancy, that amount reaches 500 to 1000 milliliters daily.24 After birth he drinks remarkably similar quantities – about 670 milliliters of milk or formula per day.25

By 19 weeks, an unborn baby's heart has beat over 20 million times.26
Visual and brain development

Although the eyelids are fused shut between 10 and 22 weeks,27 the eyes keep developing. The back of the eye, called the retina, which converts light into neural signals, now has discrete layers, each with a different function. The center of the eye matures before the outer edges.28

In animals, waves of spontaneous electrical activity cross the retinas. This allows the retinal cells to properly connect to the visual cortex in the brain, and to organize inputs from the right and left eyes.29 Although these spontaneous retinal waves have never been directly measured from the human fetus, they likely begin around this age.

By the midpoint of pregnancy, several key brain structures are beginning to take on recognizable form. Around 20 weeks, the hippocampus—a region central to memory—starts to resemble its adult structure.30 At the same time, subtle asymmetries emerge between the brain’s hemispheres, with extra growth in regions that will later process language.31 The cerebral cortex is also organizing rapidly. By this stage it has developed the six-layered structure characteristic of the newborn and adult brain, a crucial scaffold for the complex neural circuits that will support perception, thought, and learning.32

At 20 weeks, this unborn baby's vocal cords already vibrate as he silent rehearses his first cry. He will sometimes open his mouth before bringing his hands there, anticipating his own movements. (Image Credit: <a href="https://www.priestsforlife.org/graphic-images/index.aspx?gid=1&sid=1">Priests for Life</a>)
At 20 weeks, this unborn baby's vocal cords already vibrate as he silent rehearses his first cry. He will sometimes open his mouth before bringing his hands there, anticipating his own movements. (Image Credit: Priests for Life)
What can the fetus sense?

By week 20, the structures behind the sensory systems are in place if not yet fully operational. The tongue continues to grow tastebuds,33 and amniotic fluid moves through the fetal nose, allowing scents to interact with olfactory receptor neurons.34 At this point the unborn baby reacts to a touch anywhere on his body, with the possible exception of the inner thighs.35 The ear canal is open by 20 weeks, and most of the structures for detecting sound have fully formed.36 37 Research shows that the earliest an unborn baby may start to hear is around 19 weeks of pregnancy. At that age a fetus may move in response to a loud, low sound, like a car horn.38 By 20 to 21 weeks, about half of unborn children respond to a loud sound like a microwave beep with a change in heartrate.39 These reactions to external sounds reveal that the unborn baby is aware of the world outside the womb.

By 20 to 21 weeks, about half of unborn babies respond to a sound like a microwave beep with a change in heartrate.40 This shows that the baby is aware of the world outside the womb.
When does a baby start forming blood?

Although the embryo has blood by week 6 when the heart starts beating, many of the complex cells in the unborn baby’s blood, such as red and white blood cells form in different locations than they do in the adult. For example, around week 17 days after conception, red blood cells form in the umbilical vesicle. In week 5, more blood cells form near the embryonic aorta and the liver.41 42 The liver becomes the main site for blood cell production from 8 weeks until about 7 months.43 Between weeks 19 and 24, blood production gradually shifts again: bone marrow takes over making red blood cells,44 while the thymus, spleen and lymph nodes start making white blood cells.45 46 Blood cells will form in the bone marrow for the rest of the baby’s life.47

Continued development at 19 and 20 weeks gestation

Around 19 weeks of pregnancy, the fetus begins creating body fat. By 7 months, fat deposits make the baby’s cheeks chubby.48 49 At 20 weeks of pregnancy, the skin has developed hair follicles and early sweat glands.50 51

By 19 weeks, the unborn baby’s heart has beat over 20 million times.52 The fetal heart pumps about 55 quarts of blood each day.53 For comparison, that is about a tank full of gas in a small sedan.

Dive Deeper
Some babies can receive life-saving treatment while still inside the womb—long before they are even born...
If a baby is prenatally diagnosed with a fetal anomaly, the mother and baby will likely be monitored closely during pregnancy by a maternal-fetal medicine (MFM) team. However...
Sperm-egg fusion
sperm-egg fusion