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Phone: 202-223-8073
Fax: 571-312-0544

2776 S. Arlington Mill Dr.
#803
Arlington, VA 22206

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Charlotte Lozier Institute

Phone: 202-223-8073
Fax: 571-312-0544

2776 S. Arlington Mill Dr.
#803
Arlington, VA 22206

Weeks 15 & 16

Sensory systems and pain

Human Prenatal Age
  • Post-conception week 13 & 14
  • 4 Months Pregnant
  • Gestational Weeks 15 & 16
Highlights
  • There is substantial evidence that a fetus can experience pain by 15 weeks, and possibly even earlier.1

  • If a doctor took an X-ray this week, the unborn baby’s skeleton would be visible.2

  • At 15 weeks, the very first smiles have been recorded!3

Scientific advancements provide clear evidence that the fetus feels unreflective pain by 15 weeks gestation, and possibly even earlier. Unreflective pain is an immediate sensory experience of pain without necessarily knowing one is in pain.4

This composite image rendered from light-guided endoscopy recordings shows the fetus alive in the uterus at 4 months gestation. This baby can likely feel pain. (Image Credit: <a href="https://erf.science/#high-resolution">Education Resource Fund</a>)
This composite image rendered from light-guided endoscopy recordings shows the fetus alive in the uterus at 4 months gestation. This baby can likely feel pain. (Image Credit: Education Resource Fund)
When can the unborn baby feel pain?

Substantial neuroscience research concludes that the fetus can feel pain by 15 weeks. One can examine the development of pain receptors, pain neurotransmitters, and brain structures supporting the awareness of pain. While touch receptors cover almost all of the body, pain receptors develop later than regular touch receptors. Pain receptors develop from 10 to 17 weeks, starting in the hands and the area around the mouth.5 Two neurotransmitters specific to pain processing, substance P and enkephalins, have already appeared at 7 weeks.6 Furthermore, nerves connecting the primitive pain receptors with the spinal cord and thalamus can be observed as early as 15 weeks.7 While the cortex may not be fully developed, a number of brain structures that process pain activity including the brainstem, insula, and thalamus, are sufficiently mature to process pain at 15 weeks.8 Taken together, there is considerable evidence that the fetus can now feel pain.

 

There is substantial evidence that concludes an unborn baby can experience pain by 15 weeks, and possibly even earlier.9

Furthermore, researchers who have devoted their careers to the neuroscience of pain have concluded that fetal pain is possible from a very early age. Two medical professionals, one pro-choice and one pro-life came to the following conclusion:

“Overall, the evidence, and a balanced reading of that evidence, points towards an immediate and unreflective pain experience mediated by the developing function of the nervous system from as early as 12 weeks.10

 

Similarly, European neurologists and embryologists came to a similar conclusion in 2016:

“…the fetus is exposed to rudimentary painful stimuli starting from the 15th gestation week and … it is extremely sensitive to painful stimuli.11

When do babies start moving with purpose?

At 15 weeks, the unborn baby’s entire body responds to light touch with the exception of parts of the back, buttocks, and thighs.12 The baby also can move each finger separately, and often sucks his thumb. By 16 weeks, the unborn child starts grasping objects.13 14 During the first 20 weeks of pregnancy, babies sometimes lift their hands behind their heads or cross their legs, lying in poses that look remarkably like they’re relaxing in a hammock.15 Interestingly, boys and girls move differently in the womb. In fact, girls open and close their mouths more often than boys do!16

Until this point, the baby has been mostly stoic. Now the unborn child produces complex facial expressions. According to some research groups, the unborn baby can even smile!17

By about 14 weeks of gestation, movements shift from rapid, jerky motions to more controlled, targeted actions. The hands slow as they approach specific targets—most often the face—suggesting emerging motor coordination and sensory awareness. Intriguingly, in twin pregnancies, babies also modify their movements when reaching toward a sibling, indicating early sensitivity to their environment and to others nearby.18

This unborn baby can smile and suck his thumb. (Image Credit: <a href="https://www.priestsforlife.org/graphic-images/index.aspx?gid=1&sid=1">Priests for Life</a>)
This unborn baby can smile and suck his thumb. (Image Credit: Priests for Life)
During the first 20 weeks of pregnancy, babies sometimes lift their hands behind their heads or cross their legs, lying in poses that look remarkably like they're relaxing in a hammock.19
Fetal senses

By 15 weeks, the unborn baby is developing senses that will connect him to the world. The early pathways for smell, taste, touch, sight, and hearing have already taken shape. Most of the smell system is in place,20 21 and the nose can respond to irritating chemicals and touch.22 Early tastebuds have formed connections with nerves that process flavor.23 The majority of the skin is sensitive to light touches.24 The eyes have formed and the light-sensitive cells are growing in the retina.25 The ears have formed and the delicate hairs in the cochlea that will one day detect sound are forming.26

These senses start guiding behavior. By week 15, if something tickles the unborn baby’s lips, he closes his mouth and swallows. If something tickles his palm, he closes his fingers, and he can move each finger separately.27 By 15 weeks, every sensory system is actively being developed, quietly preparing this small human being for life beyond the womb.

By 15 weeks, every sensory system is partially developed, quietly preparing this small human being for life beyond the womb.
Bone development at 15 weeks gestation

The bones of the unborn child’s skeleton are made in one of two ways. Some bones, like the skull and collarbone, form directly from sheets of tissue rather than cartilage.28 Other bones start as cartilage, the same tissue that gives the outer ear its structure. As development continues, the cartilage is slowly replaced by bone cells. In a single long bone, the middle of the bone starts to harden first, and the ends keep growing longer and longer by adding cartilage. This cartilage, too, is later replaced by bone.29 By 15 weeks, if a doctor took an X-ray this week, the baby’s skeleton would be visible.30

Continued development at 15 weeks of pregnancy

By 15 weeks gestation, in the fourth month of pregnancy, the unborn baby is seen as a distinct little patient. Fetal surgery to save the life of the baby or his twin has been performed at weeks.31 32

By 15 weeks, the unborn baby can suck his thumb, and already shows a preference for his right or left hand.33 Fingerprints start forming at the center and tip of each finger, then expand across the skin.34 At 15 weeks, the basic patterns of whorls, loops, and arches of the fingerprints are established on each finger.35

The unborn baby’s heart has already beat approximately 15,800,000 times.36 The baby’s heart pumps about 26 quarts of blood per day at 15 weeks. This is like 6 and 1/2 gallons of milk. For comparison, an adult heart pumps 6,000 quarts of blood each day, which would likely fill 3 large hot tubs.37

Every body system continues advancing each week. Over weeks 15 and 16, the unborn baby grows rapidly and increases his body weight by more than half.38 39 By gestational week 15, eyebrows have formed.40

Even now, the body is preparing for the world outside the womb. Mucous glands are beginning to form in the lungs between 14 and 16 weeks gestation.41 When the baby starts breathing air after birth, the mucus will trap invading dust and germs, acting as a protective barrier to keep the lungs healthy.42 The stomach secretes digestive enzymes into swallowed amniotic fluid.43

The baby’s brain is still mostly smooth, but at 16 weeks, the first evidence of bumps can be seen.44 Grooves have already begun to form at this point as well.45 The corpus callosum, which connects the right and left sides of the brain, also begins developing as early as 15 weeks.46 47

Dive Deeper
But what exactly is a 15-week-gestation fetus like? We’ve put together 15 amazing facts about the 15-week-gestation fetus.
New research provides evidence that the fetus feels pain by 15 weeks, and possibly earlier…
5 weeks post-conception